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ESM 2010, Scientific programme
Sunday, 4.7.2010
12:00 Registration in Golf Hotel Bled
14:30-14:45 Symposium sponsored by Omega
The new 3500 series systems and MicroSEQ®, the microbial and fungi
identification system from Applied Biosystems
Chiara Reggio (Applied Biosystems)
14:45-15:00 Symposium sponsored by Cepheid
Diagnosing tuberculosis in an Italian hospital, experience with
the Xpert® MTB/RIF assay
Dr. Marta Peracchi, Microbiological laboratory, Polyclinic of Padova
15:00-15:45 Symposium sponsored by Hain Lifescience
15:45-16:30 Symposium sponsored by BD
Mycobacterial drug susceptibility testing – belief and misbelief
Prof. Erik C. Böttger, Institut für Medizinische Mikrobiologie
(Zürich, Switzerland)
Three-dimensional testing of anti-tuberculous susceptibility by the new
BD TB-eXiST method
Prof. Emmanuelle Cambau, Hôpital Saint-Louis (Paris, France)
16:30-17:00 Coffee break
17:00-17:30 Opening session at the Golf Hotel Bled:
- Organizers - Manca Žolnir-Dovč and Matjaž Ocepek
- President of ESM - Enrico Tortoli
- Director of the Golnik Clinic - Mitja Košnik
- Dean of the Veterinary Faculty Ljubljana - Marjan Kosec
- Representative of the Ministry of Health – prim. Janez Remškar
17:30-18:30 TB in the world and in Slovenia:
Co-Chairs: Suzana David and Mitja Košnik
17:30-17:50 Guest lecture: Epidemiology of tuberculosis at the global level
Véronique Vincenty
17:50-18:10 Guest lecture: Epidemiology of tuberculosis in Slovenia
Petra Svetina Šorli
18:10-18:30 Guest lecture: Eradication of bovine tuberculosis in Slovenia
Matjaž Ocepek
19:30 Welcome reception at the Bled Castle
Monday, 5.7.2010
Morning
09:00-10:30 Scientific session I: Clinical aspects of tuberculosis and
non-tuberculous mycobacterial (NTM) diseases
Co-Chairs: Gaby E. Pfyffer and Malcolm Yates
09:00-09:30 Guest lecture: Diagnostics problems of tuberculosis and NTM diseases
in the 21st century
Wiel de Lange
09:30-09:45 Tuberculosis of bones and joints
Travnik L
09:45-10:00 Automated REP-PCR based typing of nontuberculous mycobacteria
van Ingen J, de Zwaan R, van Soolingen D
10:00-10:15 Reproductive fitness of drug-resistant Mycobacterium tuberculosis
transmitted among members of different families
Morcillo N, Imperiale B
10:15-10:30 Clinical and microbiological characteristics of Nocardia isolates
in Slovenia in 2004-2009
Osolnik K, Tomič V, Žolnir-Dovč M
10:30-11:00 Coffee break
11:00-13:00 Scientific session II: Resistance and drug susceptibility testing
Co-Chairs: Sven Hoffner and Nalin Rastogi
11:00-11:30 Guest lecture: Practical experience with treatment of MDR/XDR TB
Manfred Danilovits
11:30-11:45 Performance of the GenoType® MTBDRsl assay in a high TB drug
resistance setting
Nikolayevskyy V, Balabanova Y, Kontsevaya I, Mironova S, Mitchell S,
Chinkova Y, Ignatyeva O, Fedorin I, Drobniewski F,
11:45-12:00 Combination of a cassette based fully automated DNA-isolation device with
PCR based detection of Mycobacterium tuberculosis complex and first and
second line drug susceptibility
Weizenegger M, Allerheiligen V, Lovlie R
12:00-12:15 Mutations in a transcriptional activator of Mycobacterium tuberculosis lead
to cross resistance of kanamycin and streptomycin
Zaunbrecher AM, Campbell PJH, Sultana R, Murray M, Posey JE
12:15-12:30 Mutational and physiological dynamics of drug resistance
in Mycobacterium tuberculosis
Machado D, Couto I, Rodrigues L, Amaral L, Viveiros M
12:30-12:45 Towards evidence-based breakpoints for drug susceptibility testing
of Mycobacterium tuberculosis using wild-type
minimum inhibitory concentration (MIC) distributions
Ängeby KA, Jureen P, Giske CG, Chryssanthou E, Sturegård E, Nordvall M,
Johansson AG, Werngren J, Kahlmeter G, Hoffner SE, Schön T
12:45-13:00 Wild-type distributions of MICs for anti-tuberculosis drugs, DNA sequence
and cross-resistance
Juréen P, Ängeby K, Engström A, Sturegård E, Chryssanthou E, Giske CG,
Werngren J, Nordvall M, Johansson A, Kahlmeter G, Hoffner SE, Schön T
13:00-14:00 Lunch
Afternoon
14:00-15:00 Poster session - Poster reviewers: Suzana David and Jakko van Ingen
(PP 1- 53); Alicia Aranaz and Sven Hoffner (PP 54-92); Elvira Richter and
Philip Supply (PP 93-128).
15:00-16:30 Scientific session III: Laboratory diagnostics and modern laboratory
for mycobacteria – Introduction to round table
Co-Chairs: Sabine Rüsch–Gerdes and Dick van Soolingen
15:00-15:30 Guest lecture: The role of a laboratory for mycobacteria
in veterinary medicine
Aranaz Alicia, Bezos J, Romero B, Castellanos E, Rodríguez S, Casal C,
Fernández de Mera Isabel G, Lozano F, Moya N, de Juan L, Mateos A,
Domínguez L
15:30-15:45 An integrated approach to rapid diagnosis tuberculosis
and multidrug resistance in a middle income country
Balabanova Y, Drobniewski F, Nikolayevskyy V, Kruuner A, Malomanova N,
Simak T, Ilyina N, Zakharova S, Lebedeva N, Alexander H, O’Brien R,
Sohn H, Shakhmistova A, Fedorin I
15:45-16:00 Mycobacterial microcolony detection and drug susceptibility testing
by automated monitoring of growth on solid porous supports
den Hertog AL, Visser DW, Ingham CJ, Fey FHAG, Klatser PR, Anthony RM
16:00-16:15 Defining M. tuberculosis resistance mechanisms by comparative genomics –
practical considerations and new possibilities
Feuerriegel S, Köser C, Homolka S, Niemann S
16:15-16:30 Applied nanotechnology for the detection of mycobacterial nucleic
and antigenic targets
Ikonomopoulos J, Liandris E, Andreadou M, Tachtsidis I, Gazouli M
16:30-17:00 Coffee break
17:00-18:30 Scientific session III - Round table: Modern laboratory
for mycobacteria – what can a clinician expect from it?
(Confrontation of clinicians and laboratory workers)
Co-Chairs: Francis Drobniewski and Max Salfinger
17.00-17.30 Guest lecture: Comprehensive TB laboratory services in 2010 and beyond
Max Salfinger
17.30-18.30 Round table Discussion
Proposed topics for discussion:
- Trends in laboratory diagnostics and epidemiology of TB and NTM – an insight
into the future (microarrays, sequencing, …)
- The importance of rapid laboratory diagnostics of TB
for a clinician and for preventing the transmission of TB (MDR/XDR TB)
- The importance of cooperation between different professionals
(human/veterinary medicine)
- Value of molecular epidemiology in the context of clarifying the transmission
of TB
- The role of research laboratories in solving clinical/laboratory problems
- Effect of reduced number of specimens on laboratory diagnostics (WHO)
- Value of molecular epidemiology in the context of clarifying the transmission
of TB
Moderators:
- Sabine Rüsch–Gerdes
- Véronique Vincent
- Manfred Danilovits
- Francis Drobniewski
- Wiel de Lange
- Stefan Niemann
- Nalin Rastogi
- Max Salfinger
- Jean-Pierre Zellweger
19:30 National evening - Panorama Bled restaurant
Tuesday, 6.7.2010
Morning
09:00-11:00 Scientific session IV: Ecology of mycobacteria and veterinary
mycobacteriology
Co-Chairs: Alicia Aranaz and Enrico Tortoli
09:00-09:30 Guest lecture: Ecology of mycobacteria
Ivo Pavlik
09:30-10:00 Guest lecture: Paratuberculosis: An overview
Norma Arrigoni
10:00-10:15 Spanish database of animal mycobacteriosis (MYCODB):
application in epidemiological studies
de Juan L, Rodríguez S, Romero B, Aranaz A, Bezos J, Castellanos E,
González S, Sáez JL, Mateos A, Domínguez L
10:15-10:30 Validation of molecular typing for Mycobacterium avium subsp.
paratuberculosis (MAP)
Fritsch I, Köhler H, Möbius P
10:30-10:45 Diagnosis of Mycobacterium bovis infection in bovine and non-bovine species
in Great Britain
Brewer J
10:45-11:00 A simple and inexpensive liquid culture method for the diagnosis of
bovine paratuberculosis
Stefani E, Gwozdz J, Gastaldelli M, Capello K, Tondo A, Valente A, Pozzato N
11:00-11:30 Coffee break
11:30-12:15 Scientific session V: Mycobacteria in Crohn’s disease
Co-Chairs: Tim Bull and Ivo Pavlik
11:30-12:00 Guest lecture: Mycobacterium avium subspecies paratuberculosis and
Crohn’s disease
Tim Bull
12:00-12:15 Exploring the aetiology of Crohn’s disease through comparative genomics of
Mycobacterium avium subsp. paratuberculosis
Wynne JW, Seemann T, Bulach DM, Wagner J, Kirkwood CD, Michalski WP
12:15-13:30 Scientific session VI: Biosafety and quality control
Co-Chairs: Christophe Sola and Lothar Binder
12:15-12:45 Guest lecture: Biosafety in TB laboratories
Véronique Vincent
12:45-13:00 Practical training on growth detection and drug susceptibility testing of TB in
resource poor settings to absorb new diagnostic tests
Somoskovi A, Gutierrez CM, Paramasivan CN, Parsons L
13:00-13:15 Quality control and biosafety in a TB facility
Šprajcar D
13:15-13:30 Aerosol production and dissemination and implications for Public Health
McNerney R, Lai K-M
13:30-14:15 Lunch
Afternoon
14:15-15:00 Poster session
Poster reviewers: Suzana David and Jakko van Ingen (PP 1- 53); Alicia Aranaz
and Sven Hoffner (PP 54-92); Elvira Richter and Philip Supply (PP 93-128).
15:00-15:30 Presentations of the best posters
16:00 Trip to Postojna Cave
19:00-20:00 General assembly at the Restaurant Jamski dvorec Postojna
20:00 Dinner
Wednesday, 7.7.2010
Morning
09:00-11:00 Scientific session VII: Epidemiology
Co-Chairs: Stefan Niemann and Philip Supply
09:00-09:30 Guest lecture: Universal genotyping of M. tuberculosis in the United States
Lauren S Cowan
09:30-09:45 The molecular epidemiology of tuberculosis in Europe
van Soolingen D, Schürch A, de Beer J, Verhagen L, van Ingen J, Kremer K
09:45-10:00 Deciphering the biological meaning of the IS6110 insertion element
Sandoval A, Reyes A, Cubillos A, Ritacco V, López B, Robledo J, Samper S,
Martin C, García MJ, Zambrano MM, Mitra R, Del Portillo P
10:00-10:15 The study of transmission of MDR-TB in Europe as indicator of what happens
in TB high-endemic countries
Gavín P, Iglesias MJ, Lezcano MA, Jiménez MS, Rodríguez-Valín E, Martin C,
Samper S, the Spanish Working Group on MDR-TB
10:15-10:30 Evaluation of sequence data for the phylogenetic classification of
the Mycobacterium tuberculosis complex
Projahn M, Homolka S, Rüsch-Gerdes S, Diel R, Niemann S
10:30-10:45 A novel genetic marker reveals human tuberculosis caused by
“antelope clade” bacteria
van Ingen J, Mulder A, Brosch R, van Soolingen D
10:45-11:00 Molecular epidemiology underlines the importance of Mycobacterium caprae
in livestock and wildlife
Rodríguez S, Bezos J, de Juan L, Romero B, Álvarez J, Castellanos E,
González S, Sáez JL, Mateos A, Domínguez L, Aranaz A
11:00-11:30 Coffee break
11:30-13:15 Scientific session VIII: Immunology/Drug development/Diagnostics
Co-Chairs: Vera Katalinić–Janković and Jean-Pierre Zellweger
11:30-12:00 Guest lecture: IGRA tests: Where are we today?
Jean-Pierre Zellweger
12:00-12:15 Resolving lineage assignation on Mycobacterium tuberculosis clinical isolates
classified by spoligotyping with a new high throughput SNPs-based method
Abadia E, Zhang J, Dos Vultos T, Ritacco V, Kremer K, Aktas E,
Matsumoto T, Refregier G, van Soolingen D, Gicquel B, Sola C
12:15-12:30 Translating into practice line probe assay training for MDR-TB screening in
high burden countries: lessons from the field
Gutierrez C, Marinus B, Paramasivan CN, Somoskovi A
12:30-12:45 Identification of non-tuberculous mycobacteria by sequencing a fragment of
the 16S rRNA gene: Which internet database to be used to analyse
the sequence?
Mathys V, Vanfleteren B, Fauville-Dufaux M
12:45-13:00 Drug resistance patterns of treatment failure in hospitalized TB patients
of Bangladesh
Rahim Z, Khan SS, Nakajima C, van der Zanden AGM, Suzuki Y
13:00-13:15 Management of tuberculosis outbreaks
Miranda A, Alves A, Tavares Magalhães A, Duarte R, Correia A
13:15-13:30 Closing remarks
13:30-13:45 CLOSING OF CONGRESS
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University Clinic of Pulmonary and Allergic Diseases Golnik |
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Veterinary Faculty |
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Hain Lifescience |
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BD Diagnostics |
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Cepheid |
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Iris |
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Sava hotels&resorts |
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Applied Maths |
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Mediline |
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Cellestis |
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Microsens |
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Alpha Tec |
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Tehnooptika |
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Iskra PIO |
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Mikro+Polo |
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BioMerieux |
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Sanofi Aventis |
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Ewopharma |
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Sanolabor |
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Kemomed |
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LKB |
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Omega |
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Genoscreen |
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Krka |
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Mettler Toledo |
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Boehringer Ingelheim |
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Pfizer |
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Simps'S |
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